Experiment 140833
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Unidentified fungus (UNDETERMINED) |
| Citation | BERGSTROM,JD: KURTZ,MM: REW,DJ: AMEND,AM: KARKAS,JD: BOSTEDOR,RG: BANSAL,VS: DUFRESNE,C: VAN MIDDLESWORTH,FL: HENSENS,OD: LIESCH,JM: ZINK,DL: WILSON,KE: ONISHI,J: MILLIGAN,JA: BILLS,G: KAPLAN,L: OMSTEAD,MN: JENKINS,RG: HUANG,L: MEINZ,MS: QUINN,L: BURG,RW: KONG,YL: MOCHALES,S: MOJENA,M: AND 4 OTHERS:. (1993). ZARAGOZIC ACIDS: A FAMILY OF FUNGAL METABOLITES THAT ARE PICOMOLAR COMPETITIVE INHIBITORS OF SQUALENE SYNTHASE.. 90(1) |
| Amount utilized | |
| Compound isolated | |
| Dose amount | 6.0 MICROMOLS |
| Number | 3 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | IC50 |