Citation 69856

BERGSTROM,JD: KURTZ,MM: REW,DJ: AMEND,AM: KARKAS,JD: BOSTEDOR,RG: BANSAL,VS: DUFRESNE,C: VAN MIDDLESWORTH,FL: HENSENS,OD: LIESCH,JM: ZINK,DL: WILSON,KE: ONISHI,J: MILLIGAN,JA: BILLS,G: KAPLAN,L: OMSTEAD,MN: JENKINS,RG: HUANG,L: MEINZ,MS: QUINN,L: BURG,RW: KONG,YL: MOCHALES,S: MOJENA,M: AND 4 OTHERS:. (1993). ZARAGOZIC ACIDS: A FAMILY OF FUNGAL METABOLITES THAT ARE PICOMOLAR COMPETITIVE INHIBITORS OF SQUALENE SYNTHASE.. 90(1)

Citation Details

TitleZARAGOZIC ACIDS: A FAMILY OF FUNGAL METABOLITES THAT ARE PICOMOLAR COMPETITIVE INHIBITORS OF SQUALENE SYNTHASE.
AuthorsBERGSTROM,JD: KURTZ,MM: REW,DJ: AMEND,AM: KARKAS,JD: BOSTEDOR,RG: BANSAL,VS: DUFRESNE,C: VAN MIDDLESWORTH,FL: HENSENS,OD: LIESCH,JM: ZINK,DL: WILSON,KE: ONISHI,J: MILLIGAN,JA: BILLS,G: KAPLAN,L: OMSTEAD,MN: JENKINS,RG: HUANG,L: MEINZ,MS: QUINN,L: BURG,RW: KONG,YL: MOCHALES,S: MOJENA,M: AND 4 OTHERS:
Year1993
Volume90
Issue1

Summary

Year: 1993

Journal: Unknown

Organisms and Their Experiments (3)

Unidentified fungus (UNDETERMINED)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURECOMPOUND ISOLATED HAS UNUSUAL NAME
ZARAGOZIC ACID A
None
2
ENDOPEPTIDASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID A
ACTIVE
3
CHOLESTEROL SYNTHESIS INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID A
ACTIVE

Unidentified fungus (UNDETERMINED)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURECOMPOUND ISOLATED HAS UNUSUAL NAME
ZARAGOZIC ACID B
None
2
ENDOPEPTIDASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID B
ACTIVE
3
CHOLESTEROL SYNTHESIS INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID B
ACTIVE

Leptodontium elatius (HYPHOMYCETES)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURECOMPOUND ISOLATED HAS UNUSUAL NAME
ZAROGOZIC ACID C
None
2
CHOLESTEROL SYNTHESIS INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZAROGOZIC ACID C
ACTIVE
3
CHOLESTEROL SYNTHESIS INHIBITION
PHARMACOLOGY OF COMPOUND - IN VIVO
ZAROGOZIC ACID C
ACTIVE
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