Experiment 140838

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ZAROGOZIC ACID C

Details

PropertyValue
Pharmacology
CHOLESTEROL SYNTHESIS INHIBITION
OrganismLeptodontium elatius (HYPHOMYCETES)
CitationBERGSTROM,JD: KURTZ,MM: REW,DJ: AMEND,AM: KARKAS,JD: BOSTEDOR,RG: BANSAL,VS: DUFRESNE,C: VAN MIDDLESWORTH,FL: HENSENS,OD: LIESCH,JM: ZINK,DL: WILSON,KE: ONISHI,J: MILLIGAN,JA: BILLS,G: KAPLAN,L: OMSTEAD,MN: JENKINS,RG: HUANG,L: MEINZ,MS: QUINN,L: BURG,RW: KONG,YL: MOCHALES,S: MOJENA,M: AND 4 OTHERS:. (1993). ZARAGOZIC ACIDS: A FAMILY OF FUNGAL METABOLITES THAT ARE PICOMOLAR COMPETITIVE INHIBITORS OF SQUALENE SYNTHASE.. 90(1)
Amount utilized
Compound isolated
Dose amount4.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50