Experiment 180824

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

RAPAMYCIN,9-DEOXO-27-DEMETHOXY-39-O-DEMETHYL:

Details

PropertyValue
Pharmacology
IMMUNOSUPPRESSANT ACTIVITY
OrganismActinoplanes species (ACTINOPLANACEAE)
CitationNISHIDA,H: SAKAKIBARA,T: AOKI,F: SAITO,T: ICHIKAWA,K: INAGAKI,T: KOJIMA,Y: YAMAUCHI,Y: HUANG,LH: GUADLIANA,MA: KANEKO,T: KOJIMA,N:. (1995). GENERATION OF NOVEL RAPAMYCIN STRUCTURES BY MICROBIAL MANIPULATIONS.. 48(7)
Amount utilized
Compound isolated
DiseaseMIXED LYMPHOCYTE REACTION.
Dose amount>1.8 MICROMOLS
Number25
Qualitative resultWEAK ACTIVITY
AnimalHUMAN ADULT
Dose expressionIC50