Experiment 181543

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

XESTOQUINONE,14-CHLORO-15-HYDROXY:

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismXestospongia species (PETROSIIDAE)
CitationCONCEPCION,GP: FODERARO,TA: ELDREDGE,GS: LOBKOVSKY,E: CLARDY,J: BARROWS,LR: IRELAND,CM:. (1995). TOPOISOMERASE II-MEDIATED DNA CLEAVAGE BY ADOCIA- AND XESTOQUINONES FROM THE PHILIPPINE SPONGE XESTOSPONGIA SP.. 38(22)
Amount utilized
Compound isolated
DiseaseASSAYED WITH 15-CHLORO-14-HYDROXY-XESTOQUINONE.
Dose amount33.0 MICROMOLS
Number30
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50