Experiment 189596

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SPORORMIELLA ANTIBIOTIC L-731120

Details

PropertyValue
Pharmacology
SQUALENE SYNTHASE INHIBITION
OrganismSporormiella intermedia (PHAEOTRICHACEAE)
CitationHARRIS,GH: DUFRESNE,C: JOSHUA,H: KOCH,LA: ZINK,DL: SALMON,PM: GOKLEN,KE: KURTZ,MM: REW,RJ: BERGSTROM,JD: WILSON,KE:. (1995). ISOLATION, STRUCTURE DETERMINATION AND SQUALENE SYNASE ACTIVITY OF L-731,120 AND L-731,128, ALKY CITRATE ANALOGS OF ZARAGOZIC ACIDS A AND B.. 5(20)
Amount utilized
Compound isolated
Dose amount260.0 NANOMOLS
Number7
Qualitative resultACTIVE
AnimalRAT
Dose expressionIC50