Citation 76685

HARRIS,GH: DUFRESNE,C: JOSHUA,H: KOCH,LA: ZINK,DL: SALMON,PM: GOKLEN,KE: KURTZ,MM: REW,RJ: BERGSTROM,JD: WILSON,KE:. (1995). ISOLATION, STRUCTURE DETERMINATION AND SQUALENE SYNASE ACTIVITY OF L-731,120 AND L-731,128, ALKY CITRATE ANALOGS OF ZARAGOZIC ACIDS A AND B.. 5(20)

Citation Details

Title	ISOLATION, STRUCTURE DETERMINATION AND SQUALENE SYNASE ACTIVITY OF L-731,120 AND L-731,128, ALKY CITRATE ANALOGS OF ZARAGOZIC ACIDS A AND B.
Authors	HARRIS,GH: DUFRESNE,C: JOSHUA,H: KOCH,LA: ZINK,DL: SALMON,PM: GOKLEN,KE: KURTZ,MM: REW,RJ: BERGSTROM,JD: WILSON,KE:
Year	1995
Volume	5
Issue	20

Summary

Year: 1995

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	SQUALENE SYNTHASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AGARICIC ACID	WEAK ACTIVITY
2	CHOLESTEROL INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	AGARICIC ACID	INACTIVE

Sporormiella intermedia (PHAEOTRICHACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	ZARAGOZIC ACID B	None
2	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	ZARAGOZIC ACID A	None
3	SQUALENE SYNTHASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ZARAGOZIC ACID A	STRONG ACTIVITY
4	CHOLESTEROL INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	ZARAGOZIC ACID A	ACTIVE
5	CHOLESTEROL INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	ZARAGOZIC ACID A	WEAK ACTIVITY
6	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	SPORORMIELLA ANTIBIOTIC L-731120	None
7	SQUALENE SYNTHASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	SPORORMIELLA ANTIBIOTIC L-731120	ACTIVE
8	CHOLESTEROL INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	SPORORMIELLA ANTIBIOTIC L-731120	WEAK ACTIVITY
9	CHOLESTEROL INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	SPORORMIELLA ANTIBIOTIC L-731120	INACTIVE
10	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	SPORORMIELLA ANTIBIOTIC L-731128	None
11	SQUALENE SYNTHASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	SPORORMIELLA ANTIBIOTIC L-731128	ACTIVE
12	Not specified	PMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	SPORORMIELLA ANTIBIOTIC L-731127	None