Experiment 189597

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

SPORORMIELLA ANTIBIOTIC L-731120

Details

PropertyValue
Pharmacology
CHOLESTEROL INHIBITION
Administration routeSC
OrganismSporormiella intermedia (PHAEOTRICHACEAE)
CitationHARRIS,GH: DUFRESNE,C: JOSHUA,H: KOCH,LA: ZINK,DL: SALMON,PM: GOKLEN,KE: KURTZ,MM: REW,RJ: BERGSTROM,JD: WILSON,KE:. (1995). ISOLATION, STRUCTURE DETERMINATION AND SQUALENE SYNASE ACTIVITY OF L-731,120 AND L-731,128, ALKY CITRATE ANALOGS OF ZARAGOZIC ACIDS A AND B.. 5(20)
Amount utilized
Compound isolated
Dose amount15.0 MG
Number8
Qualitative resultWEAK ACTIVITY
AnimalMOUSE
Per unitKG
Dose expressionED50