Experiment 252552

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC TMC-86-B

Details

PropertyValue
Pharmacology
PEPTIDYLGLUTAMYLPEPTIDE HYDROLYSIS INHIBITION
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationKOGUCHI,Y: KOHNO,J: SUZUKI,SI: NISHIO,M: TAKAHASHI,K: OHNUKI,T: KOMATSUBARA,S:. (1999). TMC-86A, B AND TMC-96, NEW PROTEASOME INHIBITORS FROM STREPTOMYCES SP. TC 1084 AND SACCHAROTHRIX SP. TC 1094. I. TAXONOMY, FERMENTATION, ISOLATION, AND BIOLOGICAL ACTIVITIES.. 52(12)
Amount utilized
Compound isolated
Dose amount31.0 MICROMOLS
Number14
Qualitative resultWEAK ACTIVITY
Dose expressionIC50