Experiment 252558

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC TMC-86-B

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationKOGUCHI,Y: KOHNO,J: SUZUKI,SI: NISHIO,M: TAKAHASHI,K: OHNUKI,T: KOMATSUBARA,S:. (1999). TMC-86A, B AND TMC-96, NEW PROTEASOME INHIBITORS FROM STREPTOMYCES SP. TC 1084 AND SACCHAROTHRIX SP. TC 1094. I. TAXONOMY, FERMENTATION, ISOLATION, AND BIOLOGICAL ACTIVITIES.. 52(12)
Amount utilized
Compound isolated
Dose amount0.43 MICROMOLS
Number20
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50