Experiment 366706

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ZARAGOZIC ACID D-3

Details

PropertyValue
Pharmacology
SQUALENE SYNTHASE INHIBITION
OrganismMollisia species (DERMATEACEAE)
CitationTANIMOTO,T: HAMANO,K: ONODERA,K: HOSOYA,T: KAKUSAKA,M: HIRAYAMA,T: SHIMADA,Y: KOGA,T: TSUJITA,Y:. (1997). BIOLOGICAL ACTIVITIES OF NOVEL ZARAGOZIC ACIDS, THE POTENT INHIBITORS OF SQUALENE SYNTHASE, PRODUCED BY THE FUNGUS, MOLLISIA SP.SANK 10294.. 50(5)
Amount utilized
Compound isolated
Dose amount0.7 NANOMOLS
Number2
Qualitative resultSTRONG ACTIVITY
AnimalRAT
Dose expressionIC50
GenderMALE