Citation 104281

TANIMOTO,T: HAMANO,K: ONODERA,K: HOSOYA,T: KAKUSAKA,M: HIRAYAMA,T: SHIMADA,Y: KOGA,T: TSUJITA,Y:. (1997). BIOLOGICAL ACTIVITIES OF NOVEL ZARAGOZIC ACIDS, THE POTENT INHIBITORS OF SQUALENE SYNTHASE, PRODUCED BY THE FUNGUS, MOLLISIA SP.SANK 10294.. 50(5)

Citation Details

TitleBIOLOGICAL ACTIVITIES OF NOVEL ZARAGOZIC ACIDS, THE POTENT INHIBITORS OF SQUALENE SYNTHASE, PRODUCED BY THE FUNGUS, MOLLISIA SP.SANK 10294.
AuthorsTANIMOTO,T: HAMANO,K: ONODERA,K: HOSOYA,T: KAKUSAKA,M: HIRAYAMA,T: SHIMADA,Y: KOGA,T: TSUJITA,Y:
Year1997
Volume50
Issue5

Summary

Year: 1997

Journal: Unknown

Organisms and Their Experiments (1)

Mollisia species (DERMATEACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
ISOLATION AND IDENTIFICATION OF
ZARAGOZIC ACID D-3
None
2
SQUALENE SYNTHASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID D-3
STRONG ACTIVITY
3
STEROL SYNTHESIS INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID D-3
STRONG ACTIVITY
4
CHOLESTEROL LEVEL DECREASE
PHARMACOLOGY OF COMPOUND - IN VIVO
ZARAGOZIC ACID D-3
ACTIVE
5
CHOLESTEROL LEVEL DECREASE
PHARMACOLOGY OF COMPOUND - IN VIVO
ZARAGOZIC ACID D-3
WEAK ACTIVITY
6Not specified
ISOLATION AND IDENTIFICATION OF
ZARAGOZIC ACID B
None
7
SQUALENE SYNTHASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID B
STRONG ACTIVITY
8
STEROL SYNTHESIS INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID B
STRONG ACTIVITY
9
CHOLESTEROL LEVEL DECREASE
PHARMACOLOGY OF COMPOUND - IN VIVO
ZARAGOZIC ACID B
ACTIVE
10Not specified
ISOLATION AND IDENTIFICATION OF
ZARAGOZIC ACID C
None
11
SQUALENE SYNTHASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID C
STRONG ACTIVITY
12Not specified
ISOLATION AND IDENTIFICATION OF
ZARAGOZIC ACID D
None
13
SQUALENE SYNTHASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ZARAGOZIC ACID D
STRONG ACTIVITY
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