Experiment 366717

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ZARAGOZIC ACID D

Details

PropertyValue
Pharmacology
SQUALENE SYNTHASE INHIBITION
OrganismMollisia species (DERMATEACEAE)
CitationTANIMOTO,T: HAMANO,K: ONODERA,K: HOSOYA,T: KAKUSAKA,M: HIRAYAMA,T: SHIMADA,Y: KOGA,T: TSUJITA,Y:. (1997). BIOLOGICAL ACTIVITIES OF NOVEL ZARAGOZIC ACIDS, THE POTENT INHIBITORS OF SQUALENE SYNTHASE, PRODUCED BY THE FUNGUS, MOLLISIA SP.SANK 10294.. 50(5)
Amount utilized
Compound isolated
Dose amount2.0 NANOMOLS
Number13
Qualitative resultSTRONG ACTIVITY
AnimalRAT
Dose expressionIC50
GenderMALE