Experiment 497976

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DIDEMNIN B

Details

PropertyValue
Pharmacology
PROTEIN SYNTHESIS INHIBITION DURING ELONGATION PROCESS
OrganismEmpty organism
CitationCREW,CM: COLLINS,JL: LANE,WS: SNAPPERS,ML: SCHREIBER,SL:. (1994). GTP-DEPENDENT BINDING OF THE ANTIPROLIFERATIVE AGENT DIDEMNIN TO ELONGATION FACTOR 1A.. 269(22)
Amount utilized
Compound isolated
DiseaseCMPD FOUND TO BIND TO ELONGATION FACTOR-1 ALPHA(GPT), BUT DID NOT INHIBIT GTP HYDROLYSIS.
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED