DIDEMNIN B (35612)

Name	DIDEMNIN B
Compound class	75102BBE7HH162027283565707785
Compound code	MACROCYCLIC LACTAM-LACTONE

Experiment	Worktypes	Pharmacology	Organism (specimen)
1184975	PHARMACOLOGY OF COMPOUND - IN VIVO	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1175140	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Trididemnum species (DIDEMNIDAE)
1175139	ISOLATION AND IDENTIFICATION OF		Trididemnum species (DIDEMNIDAE)
666347	PHARMACOLOGY OF COMPOUND - IN VITRO	ANTIPROLIFERATION ACTIVITY	Empty organism
1189336	STRUCTURE DETERMINATION OFCORRECTION OF STRUCTURECOMPLETE SYNTHESIS REPORTED		Empty organism
497976	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION DURING ELONGATION PROCESS	Empty organism
665896	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
1010775	ISOLATION OF A COMPOUND WITH NOVEL STRUCTURE		Trididemnum species (DIDEMNIDAE)
538736	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
868536	CORRECTION OF STRUCTURE		Empty organism
1175145	PHARMACOLOGY OF COMPOUND - IN VIVO	ALLOGRAFT REJECTION INHIBITION	Trididemnum species (DIDEMNIDAE)
1171663	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
1184984	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
650683	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Empty organism
694281	PHARMACOLOGY OF COMPOUND - IN HUMANS	ANTITUMOR ACTIVITY	Empty organism
1140752	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	RNA SYNTHESIS INHIBITION	Empty organism
670859	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
1184971	PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1175144	PHARMACOLOGY OF COMPOUND - IN VITRO	LYMPHOCYTE BLASTOGENESIS INHIBITION	Trididemnum species (DIDEMNIDAE)
666350	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Empty organism
1171666	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
665895	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
1184981	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
908814	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
686524	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
1184978	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
715226	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Empty organism
1184974	PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1184985	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
1164716	PHARMACOLOGY OF COMPOUND - IN VIVO	THROMBOCYTOPENIC ACTIVITY	Empty organism
666348	PHARMACOLOGY OF COMPOUND - IN VITRO	ANTIPROLIFERATION ACTIVITY	Empty organism
497977	PHARMACOLOGY OF COMPOUND - IN VITRO	CELL PROLIFERATION INHIBITION	Empty organism
944748	COMPLETE SYNTHESIS REPORTED		Empty organism
561779	PHARMACOLOGY OF COMPOUND - IN VITRO	APOPTOSIS INDUCTION	Empty organism
670858	PHARMACOLOGY OF COMPOUND - IN VITRO	PALMITOYL PROTEIN THIOESTERASE 1 INHIBITION	Empty organism
1184970	PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1140751	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DNA SYNTHESIS INHIBITION	Empty organism
694283	PHARMACOLOGY OF COMPOUND - IN HUMANS	TOXIC EFFECT(GENERAL)	Empty organism
669495	PHARMACOLOGY OF COMPOUND - IN HUMANS	ANTITUMOR ACTIVITY	Empty organism
1171667	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
742587	SYNTHESIS OF ANALOGS		Empty organism
666349	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Empty organism
650685	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Empty organism
116574	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CROWN GALL TUMOR INHIBITION	Empty organism
1171967	PATENT DESCRIBEDISOLATION AND IDENTIFICATION OF		Trididemnum species (DIDEMNIDAE)
1175143	PHARMACOLOGY OF COMPOUND - IN VITRO	LYMPHOCYTE BLASTOGENESIS INHIBITION	Trididemnum species (DIDEMNIDAE)
654923	PHARMACOLOGY OF COMPOUND - IN VITRO	APOPTOSIS INDUCTION	Empty organism
1184982	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
908815	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
1184968	ISOLATION AND IDENTIFICATION OF		Trididemnum species (DIDEMNIDAE)
954945	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
595946	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
1184979	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
1171665	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
1184986	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
650686	PHARMACOLOGY OF COMPOUND - IN VITRO	NEURITE SPROUTING INHIBITION	Empty organism
1164715	PHARMACOLOGY OF COMPOUND - IN VIVO	PROTHROMBIN TIME INCREASED	Empty organism
665894	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
1192438	X-RAY CHRYSTALLOGRAPHIC STUDIES		Empty organism
654921	PHARMACOLOGY OF COMPOUND - IN VITRO	CELL PROLIFERATION INHIBITION	Empty organism
1184969	PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1184983	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
1140754	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
1184973	PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1171671	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
184333	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Trididemnum cyanophorum (DIDEMNIDAE)
704123	SYNTHESIS OF ANALOGS		Empty organism
715227	PHARMACOLOGY OF COMPOUND - IN VITRO	IMMUNOSUPPRESSANT ACTIVITY	Empty organism
945335	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	REVERSE TRANSCRIPTASE INHIBITION	Empty organism
694282	PHARMACOLOGY OF COMPOUND - IN HUMANS	ANTITUMOR ACTIVITY	Empty organism
889087	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
866527	COMPLETE SYNTHESIS REPORTED		Empty organism
1140750	PHARMACOLOGY OF COMPOUND - IN VITRO	MEMBRANE PERMEABILITY ENHANCEMENT	Empty organism
1171668	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
418614	PHARMACOLOGY OF COMPOUND - IN VITRO	REVERSE TRANSCRIPTASE INHIBITION	Empty organism
665897	PHARMACOLOGY OF COMPOUND - IN VITRO	PROTEIN SYNTHESIS INHIBITION	Empty organism
1175142	PHARMACOLOGY OF COMPOUND - IN VITRO	RNA SYNTHESIS INHIBITION	Trididemnum species (DIDEMNIDAE)
1184976	PHARMACOLOGY OF COMPOUND - IN VIVO	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
556414	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODEREVIEW OF	ANTITUMOR ACTIVITY	Empty organism
908813	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
636169	PHARMACOLOGY OF COMPOUND - IN VITRO	APOPTOSIS INDUCTION	Empty organism
1140753	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PROTEIN SYNTHESIS INHIBITION	Empty organism
1171670	PHARMACOLOGY OF COMPOUND - IN VITRO	RNA SYNTHESIS INHIBITION	Empty organism
530038	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
654922	PHARMACOLOGY OF COMPOUND - IN VITRO	CELL CYCLE CYTOTOXICITY(S PHASE)	Empty organism
650684	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Empty organism
1024735	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
880360	PHARMACOLOGY OF COMPOUND - IN HUMANS	TOXIC EFFECT(GENERAL)	Empty organism
440908	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
661568	PHARMACOLOGY OF COMPOUND - IN VITRO	PALMITOYL PROTEIN THIOESTERASE 1 INHIBITION	Empty organism
585589	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
565334	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
1184972	PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
1175141	PHARMACOLOGY OF COMPOUND - IN VITRO	LYMPHOCYTE BLASTOGENESIS INHIBITION	Trididemnum species (DIDEMNIDAE)
1184977	PHARMACOLOGY OF COMPOUND - IN VIVO	TOXIC EFFECT(GENERAL)	Trididemnum species (DIDEMNIDAE)
184332	QUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Trididemnum cyanophorum (DIDEMNIDAE)
780267	PHARMACOLOGY OF COMPOUND - IN VITRO	APOPTOSIS INDUCTION	Empty organism
494925	COMPLETE SYNTHESIS REPORTED		Empty organism
1184980	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Trididemnum species (DIDEMNIDAE)
400257	SYNTHESIS OF ANALOGS		Empty organism
905122	PMR SPECTRUM REPORTEDCMR SPECTRUM REPORTED		Empty organism
530039	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism
1171664	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYTOTOXIC ACTIVITY	Empty organism
1171669	PHARMACOLOGY OF COMPOUND - IN VITRO	DNA SYNTHESIS INHIBITION	Empty organism
530037	PHARMACOLOGY OF COMPOUND - IN HUMANSANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTITUMOR ACTIVITY	Empty organism

1184975

PHARMACOLOGY OF COMPOUND - IN VIVO

TOXIC EFFECT(GENERAL)

Trididemnum species (DIDEMNIDAE)

1175140

PHARMACOLOGY OF COMPOUND - IN VITRO

PROTEIN SYNTHESIS INHIBITION

Trididemnum species (DIDEMNIDAE)

1175139

ISOLATION AND IDENTIFICATION OF

Trididemnum species (DIDEMNIDAE)

666347