Experiment 661568

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DIDEMNIN B

Details

PropertyValue
Pharmacology
PALMITOYL PROTEIN THIOESTERASE 1 INHIBITION
OrganismEmpty organism
CitationMENG,L: SIN,N: CREWS,CM:. (1998). THE ANTIPROLIFERATIVE AGENT DIDEMNIN B UNCOMPETITIVELY INHIBITS PALMITOYL PROTEIN THIOESTERASE.. 37(29)
Amount utilized
Compound isolated
DiseaseVS.HUMAN PTI WITH [3H]-HA-RAS.ASSAY.
Dose amount5.0 MICROMOLS
Number1
Qualitative resultACTIVE
Dose expressionIC50