Experiment 517207

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SPONGIASTATIN 1

Details

PropertyValue
Pharmacology
ANTIMITOTIC ACTIVITY
OrganismEmpty organism
CitationBAI,R: CICHACZ,ZA: HERALD,CL: PETTIT,GR: HAMEL,E:. (1993). SPONGISTATIN 1, A HIGHLY CYTOTOXIC, SPONGE-DERIVED, MARINE NATURAL PRODUCT THAT INHIBITS MITOSIS, MICROTUBULE ASSEMBLY, AND THE BINDING OF VINBLASTINE TO TUBULIN.. 44(4)
Amount utilized
Compound isolated
Dose amount0.02 NANOMOLS
Number1
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50