Experiment 536019

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SPONGIASTATIN 3

Details

PropertyValue
Pharmacology
TUBULIN BINDING INHIBITION
OrganismEmpty organism
CitationBAI,R: TAYLOR,GF: CICHACZ,ZA: HERALD,CL: KEPLER,JA: PETTIT,GR: HAMEL,E:. (1995). THE SPONGIASTATINS, POTENTLY CYTOTOXIC INHIBITORS OF TUBULIN POLYMERIZATION, BIND IN A DISTINCT REGION OF THE VINCA DOMAIN.. 34(30)
Amount utilized
Compound isolated
DiseaseVS.DOLASTATIN 10 BINDING.
Dose amount5.0 MICROMOLS
Number15
Qualitative resultWEAK ACTIVITY
Dose expressionCONC USED