Experiment 74816

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

THIOCOLCHICINE,2-DEMETHYL:

Details

PropertyValue
Pharmacology
TUBULIN BINDING EFFECT
OrganismEmpty organism
CitationKEREKES,P: SHARMA,PN: BROSSI,A: CHIGNELL,CF: QUINN,FR:. (1985). SYNTHESIS AND BIOLOGICAL EFFECTS OF NOVEL THIOCOLCHICINES. 3. EVALUATION OF N-ACYLDEACETYLTHIOCOLCHICINES, N-(ALKOXYCARBONYL) DEACETYLTHIOCOLCHICINES, AND O-ETHYLDEMETHYLTHIOCOLCHICINES. NEW SYNTHESIS OF THIODEMECOLCINE AND ANTILEUKEMIC EFFECTS OF 2-. 28(9)
Amount utilized
Compound isolated
Dose amount25.0 MICROMOLS
Number3
Qualitative resultACTIVE
AnimalRAT
Dose expressionCONC USED