Experiment 74840

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

THIOCOLCHICINE,DEACETYL: N-(TRIFLUORO-ACETYL):

Alerts

DOSING ON DAYS 1-9.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationKEREKES,P: SHARMA,PN: BROSSI,A: CHIGNELL,CF: QUINN,FR:. (1985). SYNTHESIS AND BIOLOGICAL EFFECTS OF NOVEL THIOCOLCHICINES. 3. EVALUATION OF N-ACYLDEACETYLTHIOCOLCHICINES, N-(ALKOXYCARBONYL) DEACETYLTHIOCOLCHICINES, AND O-ETHYLDEMETHYLTHIOCOLCHICINES. NEW SYNTHESIS OF THIODEMECOLCINE AND ANTILEUKEMIC EFFECTS OF 2-. 28(9)
Amount utilized
Compound isolated
Dose amount0.62 MG
Number2
Percent yield48%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS