Experiment 831035

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PODOPHYLLOTOXIN,EPI:

Details

PropertyValue
Pharmacology
TUBULIN BINDING EFFECT
OrganismEmpty organism
CitationLONG,BH: MUSIAL,ST: BRATTAIN,MG:. (1984). COMPARISON OF CYTOTOXICITY AND DNA BREAKAGE ACTIVITY OF CONGENERS OF PODOPHYLLOTOXIN INCLUDING VP16-213 AND VM26: A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP.. 23(6)
Amount utilized
Compound isolated
Dose amount12.1 MICROMOLS
Number3
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionIC50