Citation 19814

LONG,BH: MUSIAL,ST: BRATTAIN,MG:. (1984). COMPARISON OF CYTOTOXICITY AND DNA BREAKAGE ACTIVITY OF CONGENERS OF PODOPHYLLOTOXIN INCLUDING VP16-213 AND VM26: A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP.. 23(6)

Citation Details

Title	COMPARISON OF CYTOTOXICITY AND DNA BREAKAGE ACTIVITY OF CONGENERS OF PODOPHYLLOTOXIN INCLUDING VP16-213 AND VM26: A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP.
Authors	LONG,BH: MUSIAL,ST: BRATTAIN,MG:
Year	1984
Volume	23
Issue	6

Summary

Year: 1984

Journal: Unknown

Organisms and Their Experiments (11)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN	WEAK ACTIVITY
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN	ACTIVE
3	TUBULIN BINDING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ANTHRICIN	ACTIVE
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ANTHRICIN	ACTIVE
3	TUBULIN BINDING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ANTHRICIN	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ANTHRICIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI:	WEAK ACTIVITY
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI:	ACTIVE
3	TUBULIN BINDING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI:	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,EPI:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL:	ACTIVE
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL:	ACTIVE
3	TUBULIN BINDING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL:	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL:	ACTIVE
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL:	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL: GLUCOSIDE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL: GLUCOSIDE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL: GLUCOSIDE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL: GLUCOSIDE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL: BENZYLIDINE GLUCOSIDE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,4'-DEMETHYL: BENZYLIDINE GLUCOSIDE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL: BENZYLIDINE GLUCOSIDE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PODOPHYLLOTOXIN,EPI: 4'-DEMETHYL: BENZYLIDINE GLUCOSIDE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	TENIPOSIDE*	ACTIVE
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	TENIPOSIDE*	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TENIPOSIDE*	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CHROMOSOME ABERRATIONS INDUCED	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ETOPOSIDE*	ACTIVE
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ETOPOSIDE*	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ETOPOSIDE*	ACTIVE

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