Experiment 831038

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PODOPHYLLOTOXIN,4'-DEMETHYL:

Details

PropertyValue
Pharmacology
MICROTUBULE ASSEMBLY INHIBITION
OrganismEmpty organism
CitationLONG,BH: MUSIAL,ST: BRATTAIN,MG:. (1984). COMPARISON OF CYTOTOXICITY AND DNA BREAKAGE ACTIVITY OF CONGENERS OF PODOPHYLLOTOXIN INCLUDING VP16-213 AND VM26: A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP.. 23(6)
Amount utilized
Compound isolated
Dose amount0.5 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCHICKEN
Dose expressionIC50