Organism 70360 - Exostema acuminatum (RUBIACEAE)

Property	Value
Taxon	33358
Family	RUBIACEAE
Genus	EXOSTEMA
Species	ACUMINATUM
Species authority	URB.
Subspecies
Subspecies authority
Comment
Citation	ITO,A: CHAI,HB: SHIN,YG: GARCIA,R: MEJIA,M: GAO,Q: FAIRCHILD,CR: LANE,KE: MENENDEZ,AT: FARNSWORTH,NR: CORDELL,GA: PEZZUTO,JM: KINGHORN,AD:. (2000). CYTOTOXIC CONSTITUENTS OF THE ROOTS OF EXOSTEMA ACUMINATUM.. 56(35)
Geographical area	WEST INDIES
Country	DOMINICAN REPUBLIC

80 experiments

Experiment	Worktypes	Pharmacology	Organism (specimen)	Compound
258590	PHARMACOLOGY OF EXTRACT - IN VITROVOUCHER SPECIMEN REPORTED FOR	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)
258591	UV SPECTRUM GIVEN FORX-RAY CHRYSTALLOGRAPHIC STUDIESPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTUREINFRARED SPECTRUM REPORTED FOR		Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258592	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258593	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258594	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258595	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258596	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258597	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258598	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:EXOSTEMIN ICOUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258599	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:EXOSTEMIN ICOUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258600	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258601	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:KAUR-4-EN-ONE,19-NOR: 16(R)-17-DIHYDROXY: ENT:
258602	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTUREINFRARED SPECTRUM REPORTED FOR		Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258603	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258604	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258605	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258606	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258607	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258608	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258609	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258610	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258611	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	KAUR-4-EN-3-ONE,19-NOR: 16(S)-17-DIHYDROXY: ENT:
258612	CMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258613	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258614	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258615	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258616	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258617	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258618	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258619	PHARMACOLOGY OF COMPOUND - IN VIVO	ANTITUMOR ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 4'-5-7-TRIMETHOXY:
258620	CMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258621	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258622	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258623	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258624	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258625	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258626	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258627	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258628	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 5-HYDROXY-4'-7-DIMETHOXY:
258629	CMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258630	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258631	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258632	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258633	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258634	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258635	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258636	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258637	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-HYDROXY-4'-5-7-TRIMETHOXY:
258638	CMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258639	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258640	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258641	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258642	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258643	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258644	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258645	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258646	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258647	PHARMACOLOGY OF COMPOUND - IN VIVO	ANTITUMOR ACTIVITY	Exostema acuminatum (RUBIACEAE)	EXOSTEMIN I
258648	QUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258649	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258650	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258651	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258652	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258653	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258654	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258655	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258656	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258657	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258658	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-8-DIHYDROXY-4'-5-7-TRIMETHOXY:
258659	CMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION AND IDENTIFICATION OF		Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258660	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258661	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258662	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258663	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258664	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258665	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258666	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258667	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258668	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:
258669	PHARMACOLOGY OF COMPOUND - IN VITRO	CYTOTOXIC ACTIVITY	Exostema acuminatum (RUBIACEAE)	COUMARIN,4-PHENYL: 3'-5-DIHYDROXY-4'-7-DIMETHOXY:

Organism 70360 - Exostema acuminatum (RUBIACEAE)

Organism Details

Experiments

Filters

Worktypes (13)

Pharmacology (3)

Compounds (9)

Show SPARQL Queries (1)

Query 1